Hi Jon, & welcome to DC.
I'm pretty sure the answers you get will be along the lines of "set them up in whatever way feels most comfortable to you".
That is right though. The best thing to do is try out different combinations & set-ups until you find what is most comfortable, and what works best for you. What is comfortable to one person is not necessarily the same for another. It all depends on height, reach, ability, ease of movement, etc.
Have fun experimenting.
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